Cell Communication

Learning Objectives

• Describe how adenlyl cylases and phospholipase C lead to changes in cell behavior.
• Describe how cells turn off activated signaling pathways.
• Describe how steroids alter gene expression.
• Diagram how receptors activate heterotrimeric GTP-binding proteins.
• Diagram how tyrosine kinases recruit proteins to the cell membrane.
• Distinguish between paracrine and endocrine signaling.
• Given a diagram of a signaling pathway, students should be able to identify ways to manipulate the pathway to increase and decrease the strength of the pathway.