Homeostatic Control of Blood Glucose

Learning Objectives

• Students should be able to diagram how glucose triggers release of insulin in β-cells.
• Students should be able to explain how insulin secretion is triggered at glucose concentrations above 5 mM.
• Students should be able to list the metabolic and biochemical pathways that insulin affects to reduce blood glucose levels.
• Students should be able to define insulin resistance and how it manifests in skeletal muscle cells.