Leydig Cells
Leydig Cells

Leydig Cells

Interstitial or Leydig cells are located in the connective tissue surrounding the seminiferous tubules. They produce testosterone, the male sex hormone responsible for the growth and maintenance of the cells of the germinal epithelium and the development of secondary sex characteristics. Leydig cells often display cytoplasmic crystals of Reinke, the function of these crystals is unknown. Why would you expect the smooth ER to be so extensive in these cells?
Answer: Leydig cells conduct large-scale cholesterol metabolism in the production of testosterone.